We are pleased to invite you to attend a PLOS Computational Biology Symposium at the National Institutes of Health. The details of the event are as follows: “Computational Biology: Past, Present, and Future” Friday, 16th
We are excited to announce the publication of the PLOS ONE conference page. The page serves as a one-stop shop for announcements and information regarding upcoming conferences, including when and where to meet up with PLOS ONE journal staff. You … Continue reading
PLOS ONE and PLOS Biology are excited to return to the Biophysical Society’s Annual Meeting. The event will be held at the Baltimore Convention Center located in downtown Baltimore, Maryland. All are encouraged to stop by booth #636 to speak … Continue reading
The post Meet PLOS at the Biophysical Society 59th Annual Meeting appeared first on EveryONE.
PLOS ONE is excited to return to the American Geophysical Union’s Fall Meeting (AGU 2014) for a third consecutive year. The event will be held once again at the Moscone Center in downtown San Francisco, just a few blocks south … Continue reading
The National Center for Ecological Analysis and Synthesis (NCEAS) at UCSB is co-sponsoring the Open Science Codefest 2014, which aims to bring together researchers from ecology, biodiversity science, and other earth and environmental sciences with computer scientists, software engineers, and developers to collaborate on coding projects of mutual interest.
Do you have a coding project that could benefit from collaboration, or software skills you’d like to share? The codefest will be held from September 2-4 in Santa Barbara, CA.
Inspired by hack-a-thons and organized in the participant-driven, unconference style, the Open Science Codefest is for anyone with an interesting problem, solution, or idea that intersects environmental science and computer programming. This is the conference where you will actually get stuff done – whether that’s coding up a new R module, developing an ontology, working on a data repository, creating data visualizations, dreaming up an interactive eco-game, discussing an idea, or any other concrete collaborative goal that interests a group of people.
Looks like a great program!
PLOS ONE is excited for the opportunity to exhibit alongside PLOS Biology at the American Society for Cell Biology’s (ASCB) Annual Meeting in New Orleans from December 14 – 18. This year’s ASCB meeting will be held at the Ernest N. Morial Convention Center and is expected to draw approximately 7,000 cell biology enthusiasts. The conference will feature upwards of 100 scientific sessions and 2500 posters on a plethora of topics within cell biology research. Additionally, as stated on the ASCB Annual Meeting website, Nobel Laureates Randy Schekman, a PLOS ONE author, and James Rotham will be special guest speakers.
We encourage all conference attendees to stop by booth # 211 on Publisher’s Row to speak with PLOS ONE staff and learn about the journal. We look forward to engaging with PLOS ONE authors—current and prospective alike—as well as reviewers, members of our Editorial Board (Academic Editors) and all others wanting to learn about PLOS ONE and PLOS as a whole. Additionally, Dr. Ines Alvarez-Garcia, a Senior Editor from our sister journal, PLOS Biology, will be at the exhibition booth for a “meet the editor” session from noon – 1 pm on Monday, December 16. Be sure to stop by and say hello. After the conference on the evening of the 16th PLOS ONE will be hosting a mixer for all Academic Editors who are in attendance at the event. Please contact Camron Assadi (email@example.com) to RSVP.
See you in New Orleans on December 14!
In celebration of all things cell biology, here are some of the most viewed and most cited cell biology-related papers published in PLOS ONE over the past year:
Citation: Rundqvist H, Augsten M, Strömberg A, Rullman E, Mijwel S, et al. (2013) Effect of Acute Exercise on Prostate Cancer Cell Growth. PLoS ONE 8(7): e67579. doi:10.1371/journal.pone.0067579
Citation: Hanauske-Abel HM, Saxena D, Palumbo PE, Hanauske A-R, Luchessi AD, et al. (2013) Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection. PLoS ONE 8(9): e74414. doi:10.1371/journal.pone.0074414
Citation: Bhasin MK, Dusek JA, Chang B-H, Joseph MG, Denninger JW, et al. (2013) Relaxation Response Induces Temporal Transcriptome Changes in Energy Metabolism, Insulin Secretion and Inflammatory Pathways. PLoS ONE 8(5): e62817. doi:10.1371/journal.pone.0062817
Citation: Xu Y, Ding J, Wu L-Y, Chou K-C (2013) iSNO-PseAAC: Predict Cysteine S-Nitrosylation Sites in Proteins by Incorporating Position Specific Amino Acid Propensity into Pseudo Amino Acid Composition. PLoS ONE 8(2): e55844. doi:10.1371/journal.pone.0055844
Citation: Ohkura M, Sasaki T, Sadakari J, Gengyo-Ando K, Kagawa-Nagamura Y, et al. (2012) Genetically Encoded Green Fluorescent Ca2+ Indicators with Improved Detectability for Neuronal Ca2+ Signals. PLoS ONE 7(12): e51286. doi:10.1371/journal.pone.0051286
Citation: Manikkam M, Tracey R, Guerrero-Bosagna C, Skinner MK (2013) Plastics Derived Endocrine Disruptors (BPA, DEHP and DBP) Induce Epigenetic Transgenerational Inheritance of Obesity, Reproductive Disease and Sperm Epimutations. PLoS ONE 8(1): e55387. doi:10.1371/journal.pone.0055387
Image Credit: (2004) Protein Helps Orchestrate Cells’ Fluid Uptake. PLOS Biology 2(9): e318. doi:10.1371/journal.pbio.0020318.
PLOS ONE is excited to participate in the American Geophysical Union’s (AGU) Fall Meeting 2013, held this week in San Francisco’s Moscone Center. Conveniently, Moscone is just down the street from our San Francisco office, so several members of PLOS staff will be in attendance and available to chat with you about the journal. We’re looking forward to meeting both current and potential Academic Editors, reviewers, and of course authors! Please stop by Booth #301 to say hello.
Last week was a very geophysics-oriented one for us, with both the publication of Hansen et al.’s work “Assessing “Dangerous Climate Change”: Required Reduction of Carbon Emissions to Protect Young People, Future Generations and Nature” and with the announcement of our call for papers in a new collection entitled “Responding to Climate Change.” What’s more exciting is that James Hansen will be in attendance at AGU and will be giving a talk today (December 10th) on this topic, in support of taking significant, active measures to reduce fossil fuel emissions.
Last year, at AGU 2012, we were a little bit of an unfamiliar face to many. This year, we hope to continue our conversation with the physical sciences community about our commitment to open access and the publication of sound scientific research in all areas of science and medicine, including geoscience, space science, chemistry, and physics.
After AGU, look out for the PLOS booth again in just a few days at the American Society for Cell Biology!
Image Credit: Detailed view of Arctic Sea Ice in 2007, from NASA Visible Earth.
Launched in 2010, the Neuromapping and Therapeutics Collection is a unique collaboration between PLOS ONE and the Society for Brain Mapping and Therapeutics. The Neuromapping and Therapeutics Collection provides a forum for interdisciplinary research aimed at translation of knowledge across a number of fields such as neurosurgery, neurology, psychiatry, radiology, neuroscience, neuroengineering, and healthcare and policy issues that affect the treatment delivery and usage of related devices, drugs, and technologies. The Collection is open to submissions on these topics from any researcher—so far, 24 research papers have been published as part of this Collection.
We spoke to Dr. Allyson Rosen, one of the members of the Society for Brain Mapping and Therapeutics who helps coordinate the Neuromapping and Therapeutics Collection, to discuss the latest news and research in this area, and the new submissions to the collection they’re hoping to see in the next few months:
What’s exciting in Neuromapping and Therapeutics at the moment?
It is exciting to see how creative scientists and clinicians are at solving important clinical problems by combining diverse techniques in innovative ways. We see our collection as a home for cross-disciplinary work that might not “fit” in traditional journals. For example, we have published MR methods to enable effective brain infusions and work that exploits computer-aided design for cranial reconstructions. There are invasive and non-inva
What are the implications of President Obama’s commitment to Human Brain Mapping research?sive techniques for stimulating selective brain regions and creating focal lesions, such as transcranial magnetic stimulation, transcranial Doppler technology, and X-ray microplanar beam technology. There are also innovative analysis techniques that exploit powerful computational methods that were previously unavailable.
Given the high-profile nature of the Brain Mapping Initiative and the state of the US economy, we have advocated that there be some clinical implications to the announcement. We believe that this approach will ensure continued public support at a time of great need and uncertainty.
Are there any specific research areas where you’d like to see more submissions to the Collection?
We are proud of the work we’ve received and deeply impressed with the broad array of papers submitted so far. This is a testament to the creativity of our contributors, and we welcome their diversity. We particularly welcome work presented at the international meeting of the Society for Brain Mapping and Therapeutics that occurs in the spring of each year.
Why do you think it’s important to publish this kind of research in an open access journal such as PLOS ONE?
Our society is committed to being inclusive and welcoming any profession that seeks to improve the health and wellbeing of patients with brain disorders. An open access journal enables easier promotion of work we feel is important and encourages sharing among diverse disciplines. Often, truly cutting-edge work is so far ahead of its time that there is not yet an appreciation for its importance. Often, clinical problems are seen as practical but not necessarily novel. We appreciate the mission of PLOS ONE as upholding strong scientific integrity and not as triaging work based on arbitrary decisions regarding importance.
To read more about this Collection, including new research papers like, “Verifying three-dimensional skull model reconstruction using cranial index of symmetry” and “Unique anti-glioblastoma activities of Hypericin are at the crossroad of biochemical and epigenetic events and culminate in Tumor Cell Differentiation,” click here.
Come visit us at SFN 2013.
Both the Society for Brain Mapping and Therapeutics and PLOS ONE will be attending SFN 2013 – please drop by booth #136 to say hello and learn more about the Collection. For instructions on how to submit to the Collection, please visit the Collection page and download the submission document.
If you have any questions about this Collection, or any other PLOS Collections, please email firstname.lastname@example.org
Image credit for Collection cover: Alka Joshi
PLOS is at SpotOn London (#solo13) again this year, taking part in workshops and panels on science communication tools, policy, and outreach. On Friday November 8, I’ll be joined by three PLOS authors and two independent science journalists for a science outreach workshop titled Public Health Links, Lost in Translation. With our moderator, science journalist Suzi Gage (@soozaphone) of the Sifting the Evidence blog on The Guardian, we will address weak links in the science communication “food chain” that contribute to falling vaccination rates, mainly in the UK, Europe, and the US.
For this session, I will be speaking as Editorial Director of PLOS ONE, the world’s largest scientific journal. But the debate around vaccination began before PLOS existed and it has gone on longer than I’ve been involved in science communication. Coming as I do from a background of ‘peddling the evidence,’ it disturbs me when I see evidence ignored in favour of quackery. But I also bring a personal perspective to this issue. As with climate change, it frustrates me that my own actions are not enough to safeguard my children against a threat to their health and safety. Although no vaccine is perfect, every time my children play with others who are intentionally un-vaccinated their risk of contracting preventable contagious diseases increases.
So it seems to me that the aim of this workshop will be to use our combined perspectives – and those of the science community members present – to discuss how we strengthen the links between evidence-based science and the public on vaccines. We aren’t the first and certainly won’t be the last meeting of scientists and science writers to take on this issue, but that doesn’t let us off the hook and excuse us for not trying.
Good and Bad News
The news on vaccines in the UK is not all bad. By summer of 2013, ninety per cent of two-year-old children had received their first dose of the MMR (measles-mumps-rubella) vaccine – the highest level for 13 years according to the Health Protection Agency. This uptake in MMR vaccinations has been a public reaction to widely-reported measles outbreaks in Europe and the UK – suggesting an appropriate public response to highly visible evidence. However, present MMR uptake is still short of the 95% rate that would establish a sufficient level for herd immunity, which would stop the spread of the disease in the community.
The Legacy of MMR
All of us continue to pay the price for the broken public trust that came from the Andrew Wakefield-MMR debacle of the mid-90s. Strong distrust concerning vaccine safety exists not only in rich and middle income countries, but also on the front lines of the Global Polio Eradication Initiative, as my colleagues at PLOS Medicine have covered in depth.
The link between this widespread distrust and falling vaccination rates are clearly established:
- In 2009, one in four American parents surveyed still thought some vaccines cause autism in healthy children, and nearly one in eight have refused at least one recommended vaccine.
- The number of kindergarteners attending schools in California in which 20 or more children were intentionally unvaccinated nearly doubled from 1937 in 2008 to 3675 in 2010.
- Vaccination rates have also decreased all over Europe, resulting in measles and rubella outbreaks in France, Spain, Italy, Germany, Switzerland, Romania, Belgium, Denmark, and Turkey.
New vaccinations for diseases such as HPV, and new approaches to old ones, e.g. targeting different populations to avert new outbreaks of influenza or shingles, increase the challenges for public health practitioners and advocates.
A More Honest System
In many ways, I don’t blame the public for being mistrustful of scientific research – the scientific community and mainstream media make it very hard for people to know what to believe. As Editorial Director of a large journal, I see the entire spectrum of misinterpretation of data. I see original datasets being over-interpreted by authors, in order to get published in top journals. I see journalists taking these papers and adding yet another layer of spin in order to sell them to the public. I see newspaper editors pushing the most shocking articles to the front pages to ensure maximum impact. It’s little wonder that the public are mistrustful.
At PLOS ONE, we are trying to deal with these challenges by encouraging honest reporting of data. By removing the question of ‘novelty’ and ‘impact’ from our review process, we aim to get authors to state simply what they’ve discovered without feeling they have to dress it up in layers of over-interpretation. That drug you’ve discovered kills some cells in a petri dish. Great! Is it a cure for cancer? No. So don’t say it is – we’ll still publish your paper!
We are also very careful about what we release to the press, and how the message is put out. Clearly we can’t stop journalists misinterpreting our papers, but we can at least give the science we publish a decent chance of being reported correctly.
Finally, we track press and blog coverage and add it to the comments of the papers. Combined with our Article-level Metrics, which display a whole array of reactions to the paper and usage statistics, readers can see whether high activity on a paper is a result of heavy media attention, or whether it’s from interest from other researchers.
Certainly the papers most covered in the press are among those that receive the most views, so if we are to affect public attitudes on vaccines or any other highly-charged public health or science issue, we are as dependent on the excellent work of our authors as we are on our colleagues in new and old media. Panelists at this Friday’s SpotOn London 13 workshop represent this wide spectrum. With each bio below, I’ve included some of the research or science writing that will inform our discussion.
Marc Baguelin PhD (@marcbaguelin) is a mathematical modeler working in the Immunisation department at the Health Protection Agency and at the London School of Hygiene and Tropical Medicine on models of influenza transmission, immunization, and control. Marc’s research has been published in the journals Vaccine, Biostatistics, and Emerging Infectious Disease. His latest study, Assessing Optimal Target Populations for Influenza Vaccination Programmes: An Evidence Synthesis and Modelling Study, published in PLOS Medicine, resulted in a change of UK health policy with an extension of the influenza vaccination programme to 2-16 year old children.
Tammy Boyce, PhD (@tamboyce) holds an honorary lecturing post with the Centre for Infection Prevention and Management, Imperial College London, Hammersmith Hospital, London, and was a Research Fellow in Health, Risk, Science and Communication at the Cardiff School of Journalism. Tammy’s research has been published in Nature Reviews Immunology, and the British Journal of Healthcare Management. She was one of the first to examine public reception of media coverage and the impact the style of reporting has on public opinion and vaccination decisions. From this research, Tammy published the book Health, Risk and News: The MMR Vaccine and the Media (with Peter Lang, 2007). Her latest research article in PLOS ONE examines the role of the school nurse in addressing inequities in HPV vaccine uptake in the UK.
Stephan Lewandowsky PhD (@STWorg) is a cognitive scientist in the School of Experimental Psychology, University of Bristol, UK. His research, published in Nature Climate Change, Journal of Experimental Psychology, and Cognitive Psychology, examines peoples’ memory and decision making with particular emphasis on how people respond to corrections of misinformation. His latest PLOS ONE research article, The Role of Conspiracist Ideation and Worldviews in Predicting Rejection of Science,. studies how conspiracist thinking affects public attitudes towards scientific issues; as Hilda Bastain blogged: a “strong consensus around science can be seen as evidence that ‘they’re all in cahoots’… with vaccination, say, presenting yet more facts or another study could paradoxically confirm their rejection of science.”
Beth Skwarecki (@BethSkw) is an independent science journalist specializing in public health issues who writes for AAAS Science News, and DoubleXScience and blogs on the PLOS BLOGS Network. Recent posts have covered the HPV vaccine’s “image problem” and the role of Twitter in spreading misinformation on the 2009 H1N1 pandemic.
Here is the entire Spot On London 2013 program, FYI. Keep in mind all sessions will be live streamed with the archives kept online thereafter for your viewing.
The exceptional gigantism of sauropod dinosaurs has long been recognized as an important stage in the evolution of vertebrates, the presence of which raises questions as to why no other land-based lineage has ever reached this size, how these dinosaurs functioned as living animals, and how they were able to maintain stable populations over distinct geological periods.
We are pleased to announce the publication of a PLOS Collection featuring new research on the complex Evolutionary Cascade Theory that attempts to answer these questions and explain how the unique gigantism of sauropod dinosaurs was possible. The fourteen papers that make up the collection address sauropod gigantism from a number of varied disciplinary viewpoints, including ecology, engineering, functional morphology, animal nutrition, evolutionary biology, and paleontology.
Sauropod dinosaurs were the largest terrestrial animals to roam the earth, exceeding all other land-dwelling vertebrates in both mean and maximal body size. While convergently evolving many features seen in large terrestrial mammals, such as upright, columnar limbs and barrel-shaped trunks, sauropods evolved some unique features, such as the extremely long necks and diminutive heads they are famous for. Dr Martin Sander, Professor of Paleontology at Universität Bonn and coordinating author for this series of 14 papers, said of the collection:
“This new collection brings together the latest research on the biology of sauropod dinosaurs, the largest animals to ever walk on Earth. Having been extinct for 65 million years, reconstructing sauropod biology represents a particular challenge. Using a wide array of scientific expertise, often from seemingly unlikely fields, has led to some amazing insights. For example, principles of soil mechanics have been used to ‘weigh a dinosaur’ based on its trackways, whilst the latest in computer modeling can make a dinosaur walk again.
The ultimate question underlying this research is how sauropods were able to evolve their uniquely gigantic body size. The wide-ranging disciplines covered in the collection means that there is a -broad, multi-disciplinary audience for the research, as well as general interest in dinosaurs; therefore, we felt that it was essential to publish such a volume in a leading open-access journal such as PLOS ONE to ensure the widest possible dissemination of our work.”
Readers are able to download “Sauropod Gigantism: A Cross-Disciplinary Approach” not only as a PDF but also as an ebook (.mobi and .epub formats) from the collection page. It will also be available on Flipboard (search “PLOS Collections”).
Collection Image: Kent A. Stevens, University of Oregon